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How the Trust is working to tackle infections

This World Antibiotics Awareness Week, we bring you a list of four programmes underway to improve treatments for lung infections in cystic fibrosis (CF).

Early detection - dogs (knows) nose best

Detecting bugs early can make a big difference in the effectiveness of the treatment, otherwise the infection may become chronic and resistant to antibiotics. As part of our Personalised Approach to Pseudomonas strategic research centre, Prof Jane Davies and colleagues at Medical Detection Dogs are studying whether dogs could be used to detect early infections.

New approaches to treatment - cracking the secrets of the bug’s blueprint

Researchers working within our Innovation Hub on lung health are looking for weak spots in the armour of common bacterial infections Pseudomonas and NTM by looking at their DNA. If they can find genes that are vital for the life of the bugs, this will inform the development of the next generation of antibiotics.

How Pseudomonas lives in CF lungs – understanding its gas, food and lodging

At our UKCFC conference in September we heard from Dr Martin Welch, the principal investigator of a recently awarded SRC, who explained his plans to understand what makes the lungs of someone with CF so susceptible to developing long-term infections of Pseudomonas. You can read more about this on our website, or watch his explanation again online.

Team work makes the dream work

In September the CF Syndicate in Antimicrobial Resistance (AMR), a joint partnership between the Trust and Medicines Discovery Catapult (MDC), was launched. Its aim is to speed up the drug discovery process - from discovery of new antimicrobial drugs to reaching people with CF in the clinic, using the combined expertise of its members and the wider research community. So paraphrasing the lyric from the Chitty Chitty Bang Bang song, it's when people work together that a real difference can be made.

 Read our four pledges to support people with CF in the upcoming 2019 general election, including our continued fight against antimicrobial resistance by meeting the challenges of today and opportunities of tomorrow. Share them on social media and in person with your Parliamentary Candidates ahead of the general election on 12 December.

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